The relationship between the intracanular concentrations of unbound (free) furosemide and its natriuretic effect is in the form of a sigmoid curve with a minimum effective furosemide excretion rate of about 10 g / min. Therefore, prolonged infusion of furosemide is more effective than repeated bolus administration. In addition, if a certain bolus dose is exceeded, no significant increase in the effect is observed. When the tubular secretion of furosemide decreases or when the drug binds to the albumin located in the lumen of the tubules (for example, in a nephrotic syndrome), the effect of furosemide decreases.
Carter Rankin (Risk: Low-Moderate) - Suicide & FaithSuicide & Faith

Faith Member Background

Carter Rankin (Risk: Low-Moderate)

Carter RankinCarter Rankin is a 19-year-old African American male who has just started his sophomore year at college. During freshman year, he really enjoyed living in the dorms and meeting new people, even though his class load was challenging. In second semester, missing the ritual of attending church at home, he carved out time to get moderately involved with the youth ministries at the church on campus. He also got a part-time work study job on campus.

When he went home for the summer, his parents, Martha (58) and Jarrod (62), broke the bad news: they had sold their house and planned to move two states away in September. Carter is heartbroken: he grew up in that house and his entire high school and church community is deeply rooted in his hometown. His parents tell him the move is motivated by Martha’s new job, but Carter notices that they’re downsizing to an apartment. His older brothers Stephen (28) and Jay (26) graduated college years ago and are living successfully on their own now. Since Carter’s the last to go to college, he secretly wonders if the costs are breaking down their financial life. Carter spends the summer helping his parents pack up their house and working to earn money for books this next semester.

Carter returns to school grateful to be finished with packing, but sad to leave his childhood home for the last time, exhausted from the summer, and under a lot of pressure. If his grades don’t stay up, his scholarship will be in danger and he might also lose his work study. On the bright side, he hits it off with his new roommate (Brady, age 19), and they even share a few classes, so they can hang out and study together.

As October rolls around and midterm exams begin, Carter starts feeling extra tired, like he’s walking around with heavy chains on. He dreads getting the cheery phone calls from his parents about the fantastic new friends they’re making, and Stephen and Jay are busy with their jobs and Carter can’t always get ahold of them. After he skips youth group for the fourth time, he realizes that he might want to talk to the minister about how he’s feeling.