The relationship between the intracanular concentrations of unbound (free) furosemide and its natriuretic effect is in the form of a sigmoid curve with a minimum effective furosemide excretion rate of about 10 g / min. Therefore, prolonged infusion of furosemide is more effective than repeated bolus administration. In addition, if a certain bolus dose is exceeded, no significant increase in the effect is observed. When the tubular secretion of furosemide decreases or when the drug binds to the albumin located in the lumen of the tubules (for example, in a nephrotic syndrome), the effect of furosemide decreases.
Suicide prevention begins with recruiters, supervisors, , Feb. 3, 2011 - Suicide & Faith

Suicide Prevention in Faith Organizations: An Introduction

12.24 Suicide prevention begins with recruiters, supervisors, , Feb. 3, 2011

Army Reserve Chief Lt. Gen. Jack C. Stultz has outlined a new strategy for preventing suicide among Reserve members. At a Defense Writers Group breakfast held on February second, Stultz stated that he would like recruiters to add another question to the list of questions they ask potential recruits: “Why do you want to join the Army Reserve?” Recruiters already ask a series of questions to make sure candidates are eligible for the military, but should also make sure that potential recruits are not attempting to join in order to escape problems at home, said Stultz. Most suicides within the Army Reserve and Army National Guard occur among soldiers who have not deployed; issues such as relationship and money problems often play a role. “If we are really going to have an impact on reducing the rate of suicide in the Army Reserve, we have to get inside the soldier’s head in his civilian life – not in his military life,” said Stultz.

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