The relationship between the intracanular concentrations of unbound (free) furosemide and its natriuretic effect is in the form of a sigmoid curve with a minimum effective furosemide excretion rate of about 10 g / min. Therefore, prolonged infusion of furosemide is more effective than repeated bolus administration. In addition, if a certain bolus dose is exceeded, no significant increase in the effect is observed. When the tubular secretion of furosemide decreases or when the drug binds to the albumin located in the lumen of the tubules (for example, in a nephrotic syndrome), the effect of furosemide decreases.
SPRC updates Customized Information for Survivors - Suicide & Faith

Suicide Prevention in Faith Organizations: An Introduction

2.43 SPRC updates Customized Information for Survivors

SPRC has recently updated the Survivors web page, part of the Customized Information Series. Topics covered include self-care, helping other survivors, telling children about a suicide, preventing suicide and how and when to become active in preventing suicide after the loss of a loved one. The page also lists resources useful to survivors, such as publications, websites, and organizations.

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