The relationship between the intracanular concentrations of unbound (free) furosemide and its natriuretic effect is in the form of a sigmoid curve with a minimum effective furosemide excretion rate of about 10 g / min. Therefore, prolonged infusion of furosemide is more effective than repeated bolus administration. In addition, if a certain bolus dose is exceeded, no significant increase in the effect is observed. When the tubular secretion of furosemide decreases or when the drug binds to the albumin located in the lumen of the tubules (for example, in a nephrotic syndrome), the effect of furosemide decreases.
SAMHSA releases Mental Health, United States, 2008 - Suicide & Faith

Suicide Prevention in Faith Organizations: An Introduction

12.24 SAMHSA releases Mental Health, United States, 2008

This new publication provides a snapshot of the mental health status of the U.S. population and information on providers, settings, and types of mental health services, as well as rates of utilization, expenditures, and sources of funding for mental health services. Audiences for this report include state officials and policymakers, mental health researchers, advocacy organizations, mental health consumers, family members, and anyone interested in learning about populations served by the U.S. mental health system. Mental Health, United States 2008 includes information on suicide rates and trends by state, gender, age group, and race/ethnicity; risk factors for suicide; suicidal behavior and degree of severity; and the percentage of schools offering suicide prevention services.

For more information on this report, visit

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