The relationship between the intracanular concentrations of unbound (free) furosemide and its natriuretic effect is in the form of a sigmoid curve with a minimum effective furosemide excretion rate of about 10 g / min. Therefore, prolonged infusion of furosemide is more effective than repeated bolus administration. In addition, if a certain bolus dose is exceeded, no significant increase in the effect is observed. When the tubular secretion of furosemide decreases or when the drug binds to the albumin located in the lumen of the tubules (for example, in a nephrotic syndrome), the effect of furosemide decreases.
Out of the Darkness Community Walks Raising Needed Funds and Awareness - Suicide & Faith

Suicide Prevention in Faith Organizations: An Introduction

1.46 Out of the Darkness Community Walks Raising Needed Funds and Awareness

Over 220 Walks Taking Place Nationwide, $5.2 Million Raised to Date

Register Today at

The 2010 Out of the Darkness Community Walk campaign is in full swing, with over 220 community walks in 49 states scheduled through the fall. The walks are expected to draw more than 65,000 participants. Funds are used to support suicide prevention research, local prevention and educational programs, advocacy, and survivor of suicide loss programs in walk communities. Since 2004, the first year for these walks, these events have grown from 25 walks with 4,000 participants to today’s significant walk campaign to raise awareness and funds for suicide prevention.

For more information and to register for a 2010 Out of the Darkness Community Walk, go to

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