The relationship between the intracanular concentrations of unbound (free) furosemide and its natriuretic effect is in the form of a sigmoid curve with a minimum effective furosemide excretion rate of about 10 g / min. Therefore, prolonged infusion of furosemide is more effective than repeated bolus administration. In addition, if a certain bolus dose is exceeded, no significant increase in the effect is observed. When the tubular secretion of furosemide decreases or when the drug binds to the albumin located in the lumen of the tubules (for example, in a nephrotic syndrome), the effect of furosemide decreases.
At-a-Glance: Safe reporting on suicide - Suicide & Faith

Suicide Prevention in Faith Organizations: An Introduction

2.54 At-a-Glance: Safe reporting on suicide

A two page summary of the 2001 publication, Reporting on Suicide: Recommendations for the Media, by the Centers for Disease Control and Prevention, National Institute of Mental Health, Office of the Surgeon General, Substance Abuse and Mental Health Services Administration, American Foundation for Suicide Prevention, American Association of Suicidology and Annenberg Public Policy Center can be downloaded or viewed on-line at

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